MODULE 01
๐งฌ What Is DNA?
10 min
โผ
Inside every single cell of your body โ and there are about 37 trillion of them โ there is a twisted ladder called DNA. DNA stands for Deoxyribonucleic Acid, and it is the most incredible storage device ever discovered. It holds all the instructions needed to build you: your eye colour, how tall you grow, whether you can roll your tongue. If you stretched out all the DNA in just one of your cells, it would be about 2 metres long. And yet it is coiled so tightly it fits inside a space 200 times smaller than the width of a human hair.
โถ VIDEO
What is DNA and How Does It Work? โ Stated Clearly
A beautifully animated and crystal-clear explanation of DNA: what it is, how it's structured, and what it actually does inside your cells. Perfect starting point, age-appropriate and engaging (~10 min).
โถ Watch on YouTube โ
โ INTERACTIVE
HHMI BioInteractive: DNA Structure
Explore the double helix structure in 3D โ spin it, zoom in, and see how base pairs (A-T and G-C) fit together like puzzle pieces. From the Howard Hughes Medical Institute, one of the world's top biology education organisations.
Explore Interactive โ
DNA
Double Helix
Nucleotide
Base Pair
Adenine (A)
Thymine (T)
Guanine (G)
Cytosine (C)
If you uncoiled all the DNA from all 37 trillion cells in your body and laid it end to end, it would stretch from Earth to the Sun โ and back โ about 70 times.
MODULE 02
๐ค DNA vs RNA โ What's the Difference?
10 min
โผ
DNA is like the master recipe book, locked safely in the nucleus of your cell. But the cell's machinery โ out in the cytoplasm โ can't read it directly. That's where RNA (Ribonucleic Acid) comes in. RNA is a temporary copy of one recipe, carried out of the nucleus so the cell can build the proteins it needs. Think of DNA as the original cookbook in a library vault, and RNA as a photocopy you take to the kitchen. There are three key differences: RNA is single-stranded (not a double helix), it uses Uracil (U) instead of Thymine, and it is much shorter and disposable.
โถ VIDEO
The RNA Origin of Life
A fascinating exploration of how RNA may have been the original molecule of life โ predating DNA itself. Covers the RNA World hypothesis and why scientists believe RNA was the first self-replicating molecule on Earth (~5 min).
โถ Watch on YouTube โ
โถ VIDEO
From DNA to Protein โ HHMI BioInteractive
Watch step by step how a gene in DNA gets transcribed into mRNA, then translated into a protein by a ribosome. The central dogma of biology, beautifully animated (3 min).
โถ Watch on YouTube โ
โ INTERACTIVE
Learn.Genetics: DNA to Protein Interactive
Step through transcription and translation yourself โ build an mRNA strand from a DNA template, then use the genetic code to build a protein. Brilliant hands-on interactive from University of Utah.
Try Interactive โ
RNA
mRNA
Transcription
Translation
Ribosome
Uracil (U)
Protein
Codon
One type of COVID-19 vaccines was an mRNA Vaccine โ the first of its kind used widely in humans. Instead of putting a weakened virus into your body, it gives your cells an mRNA instruction that teaches them to recognise the virus. RNA science literally helped end a pandemic.
MODULE 03
๐ค Human Genetics โ What Makes You, You?
15 min
โผ
Your DNA contains about 3 billion base pairs โ that's the human genome. Packed inside those pairs are roughly 20,000 genes, each one an instruction for making a protein that does something in your body. But here's the wild part: 99.9% of your DNA is identical to every other human on Earth. That tiny 0.1% difference โ just 3 million base pairs โ accounts for all the variation you see between people: height, hair, blood type, even how your earwax smells. You also inherit two copies of each gene โ one from each parent โ which is why traits can skip generations or mix in unexpected ways.
โถ VIDEO
TED-Ed: How Mendel's Pea Plants Helped Us Understand Genetics
The story of Gregor Mendel, the monk who figured out inheritance using pea plants in the 1860s โ long before DNA was even discovered. A brilliant and funny history of how genetics began.
โถ Watch on YouTube โ
โ INTERACTIVE
Learn.Genetics: How Traits Are Inherited
Try the "Dragon Genetics" activity โ breed two dragons and predict what traits their offspring will inherit. Dominant and recessive genes explained visually and interactively. From the University of Utah.
Try Interactive โ
โถ VIDEO
Genetics and Heredity | Science for Kids
Surprising facts about what our genes actually do โ including why some people can taste bitter compounds others can't, and why identical twins aren't perfectly identical. Fast, fun, and full of "wow" moments (~7 min).
โถ Watch on YouTube โ
Gene
Genome
Chromosome
Dominant
Recessive
Heredity
Allele
Mutation
You share about 60% of your DNA with a banana. And about 98.7% with a chimpanzee. Evolution left its fingerprints all over life on Earth โ and the proof is in the genes.
MODULE 04
๐ฆ Evolution & How It Shapes Our DNA
15 min
โผ
Evolution is the process by which life changes over millions of years โ and DNA is the mechanism. When DNA is copied, tiny mistakes called mutations sometimes happen. Most are harmless. Some are harmful. But occasionally, a mutation gives an organism a survival advantage โ and that creature is more likely to survive, reproduce, and pass the mutation on. Over millions of generations, these changes accumulate. That's how fish became land animals, how dinosaurs became birds, and how primates became us. Every organism alive today carries DNA that has been shaped by roughly 4 billion years of evolution.
โถ VIDEO
Kurzgesagt: Evolution โ How It Actually Works
Kurzgesagt's stunning animation explains natural selection, random mutation, and how these forces drove all of life's diversity โ from single-celled ancestors to humans. One of the best evolution explainers ever made (~10 min).
โถ Watch on YouTube โ
โ INTERACTIVE
PBS Evolution: Sorting Out Evolution Interactive
Explore how natural selection works by simulating bird beak evolution. Change environments and watch which beak shapes help birds survive. Developed for PBS by WGBH Educational Foundation.
Explore Interactive โ
~4 bya
First life on Earth โ simple single-celled organisms, probably similar to modern bacteria. Their DNA was the original blueprint.
~600 mya
Multicellular animals emerge โ cells begin cooperating and specialising, guided by increasingly complex gene networks.
~375 mya
Fish crawl onto land โ key genes mutated to allow lungs, limbs, and life out of water. We still carry versions of those genes.
~6 mya
Humans and chimps diverge โ our last common ancestor lived in Africa. Since then, a small number of gene changes gave us larger brains and language.
~300,000 ya
Homo sapiens appear โ modern humans with our current genome emerge in Africa and eventually spread across the entire planet.
Today
Evolution continues โ humans are still evolving slowly. Changes in diet, environment and disease continue to shape which genes are most common.
Natural Selection
Mutation
Common Ancestor
Adaptation
Fossil Record
Speciation
The gene that makes our bones, called RUNX2, is almost identical in humans, mice, crocodiles, and sharks. Evolution is conservative โ if a gene works well, it keeps it for hundreds of millions of years.
MODULE 05
๐ How Life Science Has Changed โ CRISPR & the Future
10 min
โผ
In 1953, scientists first saw the double helix shape of DNA. In 1990, the Human Genome Project launched โ a 13-year effort to read all 3 billion letters of the human genome for the first time. It cost $2.7 billion. Today, you can have your genome sequenced for about $100. And now, scientists have a tool called CRISPR that can edit genes like a word processor edits text โ cutting out faulty letters and replacing them. It is already being used to cure inherited diseases, develop drought-resistant crops, and may one day reverse aging. Life science has gone from microscopes and pea plants to rewriting the code of life itself โ all within about 150 years.
โถ VIDEO
Kurzgesagt: Genetic Engineering Will Change Everything Forever โ CRISPR
One of the most-watched science videos ever made. Kurzgesagt explains CRISPR gene editing โ how it works, what it can cure, and the ethical questions it raises. Mind-expanding and age-appropriate (~16 min).
โถ Watch on YouTube โ
โ INTERACTIVE
Genetic Science Learning Center: Tour of the Basics
A complete interactive journey through cells, DNA, genes, proteins, heredity, and genetic technology. Built by the University of Utah โ arguably the best free genetics education site in the world for young learners.
Start Tour โ
๐ ARTICLE
Nobel Prize: The Discovery of CRISPR โ Explained for Young Readers
The Nobel Prize committee's own explanation of how Jennifer Doudna and Emmanuelle Charpentier developed CRISPR โ the tool that won the 2020 Chemistry Nobel Prize and is changing medicine forever.
Read Article โ
CRISPR
Gene Editing
Human Genome Project
Sequencing
Genetic Disease
Biotechnology
Stem Cell
In 2023, the FDA approved the first-ever CRISPR-based treatment for sickle cell disease โ a painful inherited blood disorder that affects millions of people. A single treatment, editing the patient's own bone marrow cells, may be a permanent cure.
Knowledge Check
10 questions ยท See how much you've learned!
QUESTION 01
What does DNA stand for?
QUESTION 02
Which base pairs correctly in DNA? (A pairs with __ and G pairs with __)
QUESTION 03
What is the key difference between RNA and DNA?
QUESTION 04
Approximately how many genes does the human genome contain?
QUESTION 05
How much DNA do two random humans share?
QUESTION 06
What is a mutation?
QUESTION 07
Approximately what percentage of DNA do humans share with chimpanzees?
QUESTION 08
What does CRISPR allow scientists to do?
QUESTION 09
What was the Human Genome Project?
QUESTION 10
Which scientist first proposed the idea of natural selection โ that better-adapted creatures survive and pass on their traits?